Can Chelsea break the record for the most wins? Who will make the top four? We look at the final set of Premier League questions this season.
While much of the big business at both ends has already been decided, the race for the Champions League is still very much alive as we head into the final day where each game kicks off at 3pm on Sunday.
Sky Sports will be at the heart of the action with Liverpool v Middlesbrough and Watford v Man City both shown live as they look to secure their spots ahead of Arsenal.
Ahead of the weekend, we have picked a question for each final day Premier League fixture...
Will Liverpool be making a return to the Champions League next season? (Liverpool v Middlesbrough, Sunday, 3pm live on Sky Sports 1)
Liverpool have a finish in the top four firmly in their hands, currently sitting in the final spot but just a point ahead of Arsenal as they head into the final round of fixtures.
Liverpool vs M'boro
May 21, 2017, 2:00pm
The Reds will no doubt be targeting an all-out victory against Sky Bet Championship-bound Middlesbrough to ensure they will be playing in the Champions League next season for the first time since 2014/15 campaign.
A defeat or a draw could see them slip into fifth place should Arsenal beat Everton, although they have not lost a Premier League game to Boro since February 2009.
Can Man City avoid defeat to secure a top four spot? (Watford v Man City, Sunday, 3pm live on Sky Sports 2)
Man City need just a point from their match with Watford this weekend to finish in the Premier League's top four, and the signs look good as they are unbeaten in their last seven league meetings with the Hornets.
Watford also announced that manager Walter Mazzarri will be leaving the club after the match following a horrendous run of form in recent months which could have an impact on the home side.
But for City, their aim will be to make it into the Champions League next season and they are in a strong position to do so with a victory also likely to secure them third place.
Watford vs Man City
May 21, 2017, 2:55pm
Is it too little, too late for the Gunners? (Arsenal v Everton, Sunday, 3pm)
January to April 2017 will be a period that Arsene Wenger will want to forget, but his Arsenal side have come roaring back into the top four race having won five of their last six Premier League games.
But they will need to rely on Middlesbrough to beat Liverpool or hold them to a draw and then win themselves against Everton to squeeze into fourth place.
Arsenal's run of good results could be just a little bit too late in an ultimately disappointing Premier League campaign but they will look to take the form into their FA Cup final against Chelsea on May 27.
Will Michael Keane make his final appearance for the Clarets? (Burnley v West Ham, Sunday, 3pm)
With the transfer window re-opening in a few weeks time, Burnley's Michael Keane has been subject to plenty of speculation with Man Utd reportedly interested in re-signing the England international.
Of course, the Clarets will be wanting to hang onto their prized defender who has played in 35 of the 37 Premier League games for Burnley so far this season and impressed with his performances.
But they could face some strong interest from around the Premier League with big money bids and Sunday may be the final game Keane plays in the claret of Burnley.
Can Chelsea win a record 30th Premier League game? (Chelsea v Sunderland, Sunday, 3pm)
The title has already been wrapped up by Chelsea, who will lift the Premier League trophy following Sunday's match, but they can also make some history to round off their victorious campaign.
If they beat Sunderland, they will be the first side in Premier League history to win 30 games in a season, having already matched the 29 victories recorded by the title-winning Chelsea sides of the 2004/05 and 2005/06 campaigns.
Antonio Conte's champions are arguably in a prime position to break the record, coming up against an already relegated Sunderland side who will finish the season at the bottom of the Premier League table.
Can Harry Kane snatch his second successive Golden Boot? (Hull v Tottenham, Sunday, 3pm)
It has been another fine campaign for Harry Kane, becoming only the fourth Premier League player to net 20+ goals in consecutive seasons. He now has 26 on the board after the 6-1 win over Leicester on Thursday.
This puts him top in the current list of top scorers for the 2016/17 season, two ahead of Romelu Lukaku, who has not scored in his last four league outings - his longest dry spell this term.
Third-place Alexis Sanchez (23 goals) has four goals in his last three Premier League games, but it looks as though the gong is Kane's as the England striker looks to seal another individual award.
Can the Foxes avoid an unwanted Premier League winners record? (Leicester v Bournemouth, Sunday, 3pm)
If there was ever a definition of a rollercoaster year, Leicester would be up there after the highs of winning the Premier League title last May and reaching the quarter-finals of the Champions League and the lows of Claudio Ranieri's exit and finding themselves almost dragged into a relegation battle.
Things in the middle of the table are quite congested and, of the teams to lift the Premier League trophy, Leicester could become the first to finish lower than 10th in the season following their triumph, after Chelsea finished slap bang in the middle of the pack last term.
But they could also finish as high as ninth, something Craig Shakespeare will be desperate to add to his CV if he wishes to take on the job after the summer.
Will we get a glimpse of Jose Mourinho's XI for the Europa League final? (Man Utd v Crystal Palace, Sunday, 3pm)
With Man Utd's final position of sixth in the Premier League table secured, Jose Mourinho is now turning his thoughts to the Europa League final which he has already claimed is more important than a top four finish.
A victory against Ajax on Wednesday will secure a spot in the Champions League group stages next season, and Mourinho has already been tinkering with his league side with Sergio Romero starting against Southampton in midweek.
There could be further changes and experimentation as United prepare for their Sweden showdown when they host Crystal Palace on Sunday, who themselves have secured their Premier League status for next term.
Could this be Claude Puel's final game at St Mary's? (Southampton v Stoke, Sunday, 3pm)
Rumours have been swirling over the future of Southampton manager Claude Puel in recent weeks despite the Saints remaining on course for a top eight finish and reaching the final of the EFL Cup in February.
The Frenchman has already said he will not be discussing his future until the end of the season on Sunday, but it could potentially be the final game for Puel in front of the St Mary's crowd.
Indeed, Southampton have not won any of their last four at home and have failed to score in each fixture, while Stoke have also been winless on the road in their last seven outings.
Can the Swans round off their Premier League survival with an unbeaten run? (Swansea v West Brom, Sunday, 3pm)
Swansea have seen a dramatic turnaround in form over the last few weeks. After going six games without a win, they are now unbeaten in four and have taken advantage of slip-ups by those around them to seal their Premier League status for another season.
With a victory against an out-of-sorts Baggies side on Sunday, they can go on their best winning run of the season - currently matched at two Premier League wins in a row - and end the season as high as 15th.
But West Brom will also be looking to improve their form before heading off for their summer break, having failed to win any of their last eight league games.
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